Evaluation of time profile reconstruction from complex two-color microarray designs
نویسندگان
چکیده
منابع مشابه
Robustness considerations in selecting efficient two-color microarray designs
The main goal of microarray experiments is to select a small subset of genes that are differentially expressed among competing mRNA samples. For a given set of such mRNA samples, it is possible to consider a number of two-color cDNA microarray designs with a fixed number of arrays. Appropriate criteria can be used to select an efficient design from such a set of alternative experimental designs...
متن کاملOptimal designs for 2-color microarray experiments.
Statisticians can play a crucial role in the design of gene expression studies to ensure the most effective allocation of available resources. This paper considers Pareto optimal designs for gene expression studies involving 2-color microarrays. Pareto optimality enables the recommendation of designs that are particularly efficient for the effects of most interest to biologists. This is relevan...
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گوشت قرمز یکی از مهم ترین فرآورده های دامی در تأمین پروتئین و انرژی می باشد که در حمل ویتامین های محلول در چربی نیز حائز اهمیت می باشد. انسان مانند سایر مهره داران اسید های چرب ضروری (لینولئیک و آلفا لینولنیک) مورد نیاز خود از طریق غذا تأمین می نماید. اسید های چرب ضروی پیش ساز اسید های چرب غیر اشباع با چند پیوند دوگانه هستند. اسید لینولنیک پیش ساز اسیدهای چرب امگا 3 و اسید لینولئیک نیز پیش ساز ...
Statistical Analysis of Efficient Unbalanced Factorial Designs for Two-Color Microarray Experiments
Experimental designs that efficiently embed a fixed effects treatment structure within a random effects design structure typically require a mixed-model approach to data analyses. Although mixed model software tailored for the analysis of two-color microarray data is increasingly available, much of this software is generally not capable of correctly analyzing the elaborate incomplete block desi...
متن کاملOptimal Designs for Two-Color Microarray Experiments in Multi-Factorial Models
Two-color microarray experiments form an important tool in gene expression analysis. They are often used to identify candidate genes that can be made accountable for the genesis of a certain disease. Due to the high costs of microarray experiments it is fundamental to design these experiments carefully and specifically give instructions, which samples should be allocated on the same microarray....
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2008
ISSN: 1471-2105
DOI: 10.1186/1471-2105-9-1